The painful symptoms of osteoarthritis may appear when cartilage becomes worn, and exposed bones begin to rub together. Conventional medicine does not yet have a proven treatment to stop or slow the progression of osteoarthritis. Traditional medical treatment includes drug therapy to control the pain associated with osteoarthritis. These treatments are sometimes disappointing for physicians and patients because medications may not provide complete relief and can have unwanted side effects.
Some of these patients may be candidates for nutritional supplements like glucosamine and chondroitin sulfate. Preliminary studies show glucosamine sulfate and chondroitin sulfate to be safe and well tolerated. Common side effects may include:.
These side effects are reported in a small portion of patients. However, even substances that are found naturally in the body can have unpredictable results when taken in higher than normal quantities and in different formulations.
This is particularly true with patients who are taking multiple medications or who have other diagnosed illness. For example:. Request an Appointment. Search form Search. Twitter Facebook YouTube. You are here Home Share. What is Glucosamine and Chondroitin Sulfate? Glucosamine is involved in developing tissues crucial for proper joint function.
While more studies are necessary, some research indicates that supplemental glucosamine may protect your joints from damage. This molecule has been specifically studied for its potential to treat symptoms and disease progression associated with osteoarthritis, rheumatoid arthritis and osteoporosis. Multiple studies indicate that supplementing daily with glucosamine sulfate may offer effective, long-term treatment for osteoarthritis by providing a significant reduction in pain, maintenance of joint space and overall slowing of disease progression 8 , 9 , 10 , Some studies have revealed significantly reduced markers of rheumatoid arthritis RA in mice treated with various forms of glucosamine 12 , However, study participants reported significantly improved symptom management Some early research in mice with osteoporosis also shows potential for supplemental use of glucosamine to improve bone strength While these results are encouraging, more human research is needed to understand the mechanisms of and best applications for glucosamine in joint and bone diseases.
Though glucosamine is used frequently to treat various bone and joint conditions, more research on its effects is needed. Though people use glucosamine to treat a wide variety of chronic inflammatory diseases, scientific data to support such use is limited. Glucosamine is widely promoted as a treatment for interstitial cystitis IC , a condition associated with a deficiency in the compound glycosaminoglycan.
Like interstitial cystitis, inflammatory bowel disease IBD is associated with a deficiency in glycosaminoglycan Very little research supports the notion that glucosamine can treat IBD. However, a study in mice with IBD indicated that supplementing with glucosamine may reduce inflammation Some sources claim that glucosamine may be an effective treatment for multiple sclerosis MS.
However, supporting research is lacking. One study evaluated the effect of using glucosamine sulfate alongside traditional therapy for relapsing-remitting MS.
Results showed no significant impact on relapse rate or disease progression as a result of glucosamine Some early research indicates that glucosamine sulfate may promote eye health via reduced inflammation and antioxidant effects in your retina Conversely, one small study indicated that excessive glucosamine intake may harm people with glaucoma Some sources claim that glucosamine is an effective therapy for TMJ, or temporomandibular joint.
However, research to support this claim is insufficient. One small study showed a significant reduction in pain and inflammatory markers, as well as increased jaw mobility in participants who received a combined supplement of glucosamine sulfate and chondroitin Another small study revealed no significant short-term effect of glucosamine hydrochloride supplements for people with TMJ.
However, a significant improvement in long-term pain management was reported More research is needed. While glucosamine is often regarded as an effective treatment for a wide variety of conditions, there is no conclusive data on its impact.
Currently, the strongest evidence supports glucosamine sulfate use for long-term treatment of osteoarthritis symptoms. That said, it may not work for everyone 9. In some countries — including the US — there is very little regulation of dietary supplements. Therefore, labels may be deceptive 2. Manufacturers willing to have their products tested for purity by a third party tend to have higher standards. Most research supports the use of glucosamine-sulfate solely for managing osteoarthritis symptoms.
The typical glucosamine dosage is 1, mg per day, which you can take at once or in multiple smaller doses throughout the day 2. Your shared experiences will help: - Lead to more effective treatments and outcomes - Develop programs to meet the needs of you and your community - Shape a powerful agenda that fights for you Now is the time to make your voice count, for yourself and the entire arthritis community.
Currently this program is for the adult arthritis community. Since the needs of the juvenile arthritis JA community are unique, we are currently working with experts to develop a customized experience for JA families. Get Started. As a partner, you will help the Arthritis Foundation provide life-changing resources, science, advocacy and community connections for people with arthritis, the nations leading cause of disability.
Join us today and help lead the way as a Champion of Yes. Our Trailblazers are committed partners ready to lead the way, take action and fight for everyday victories. Our Visionary partners help us plan for a future that includes a cure for arthritis. Our Pioneers are always ready to explore and find new weapons in the fight against arthritis. Our Pacesetters ensure that we can chart the course for a cure for those who live with arthritis.
Our Signature partners make their mark by helping us identify new and meaningful resources for people with arthritis. Our Supporting partners are active champions who provide encouragement and assistance to the arthritis community. Glucosamine and Chondroitin for Osteoarthritis Pain Research is mixed on whether these supplements help with OA pain and stiffness, but they are safe to try.
What Are Glucosamine and Chondroitin? How Do They Work? Which Form Is Best? Are They Safe? Complementary Therapies View All Articles. Complementary Therapies 12 Supplements for Osteoarthritis Before you buy supplements to treat your OA, see which ones have the best evidence behind them — and which do not. Complementary Therapies Hypnosis for Pain Relief Learn how this mind-body technique may help relieve arthritis symptoms. Track Your Health Share your experience with arthritis to shape research and patient care for yourself and others.
Stay in the Know. Live in the Yes. I Want to Contribute. Donate Every gift to the Arthritis Foundation will help people with arthritis across the U. Volunteer Join us and become a Champion of Yes. Live Yes! Make a Donation Help millions of people live with less pain and fund groundbreaking research to discover a cure for this devastating disease.
0コメント